If you have Type 2 diabetes and take Jardiance—or you're wondering how it works—this video explains empagliflozin and the science behind SGLT2 inhibitors in simple, straightforward terms. Jardiance works differently from many other Type 2 diabetes medications. Instead of primarily acting through insulin, it works in the kidneys, helping your body remove more glucose through urine. In this video, you'll learn how Jardiance works, why it may be prescribed, what happens if you stop taking it, how to take it, common side effects, serious safety concerns, and how it fits into an overall Type 2 diabetes treatment plan. This video focuses primarily on the use of Jardiance for Type 2 diabetes. In this video: 00:00 — Type 2 Diabetes: The Big Picture 00:18 — Why Jardiance Is Prescribed 00:44 — What Happens If You Stop Taking It? 01:03 — How Jardiance Works in the Kidneys 01:26 — How to Take Jardiance 01:48 — Jardiance Side Effects & Serious Risks 02:20 — Treatment Support & Questions to Ask 02:50 — What Is Jardiance? Final Takeaways 03:17 — Medical Disclaimer How does Jardiance work? Jardiance contains empagliflozin, an SGLT2 inhibitor. SGLT2 helps the kidneys reabsorb glucose back into the bloodstream. By blocking SGLT2, empagliflozin allows more glucose to leave the body through urine, helping lower blood glucose. SGLT2 inhibitors are also used in certain people with Type 2 diabetes who have cardiovascular or kidney-related conditions, depending on the individual's treatment plan. The FDA-approved uses and benefits depend on the specific condition and patient population. Jardiance side effects Common or important adverse effects associated with empagliflozin include increased urination, volume depletion/dehydration, urinary tract infections, and genital fungal infections. A more serious but uncommon risk is diabetic ketoacidosis (DKA). Importantly, SGLT2 inhibitor-associated DKA can sometimes occur without extremely high blood glucose levels. Symptoms can include nausea, vomiting, abdominal pain, unusual tiredness, and difficulty breathing. Seek urgent medical attention if you develop symptoms that could indicate ketoacidosis or another serious medical problem. Important Do not start, stop, or change your prescription medication based solely on information in this video. If you are sick, dehydrated, fasting, or preparing for surgery, ask your healthcare professional what you should do with your medication. Current diabetes guidance recommends specific precautions with SGLT2 inhibitors around surgery and prolonged fasting. Subscribe to Rehealthify Want straightforward explanations of diabetes medications, how they work, side effects, and the science behind your treatment? Subscribe to Rehealthify. New videos explain the medications and health topics you want to understand—without unnecessary medical jargon. Understand your medication. Understand your health. Medical Disclaimer This video is for educational and informational purposes only and is not medical advice, diagnosis, or treatment. The information presented is intended for general educational purposes and may not apply to your individual medical circumstances. Do not start, stop, discontinue, or change the dose of any prescription medication based solely on information presented in this video. Always consult your doctor, pharmacist, or other qualified healthcare professional regarding your individual treatment. If you believe you are experiencing a medical emergency, seek emergency medical care. Trademark Notice Jardiance® is a registered trademark of Boehringer Ingelheim International GmbH. This video is for independent educational purposes and is not sponsored by, endorsed by, or affiliated with Boehringer Ingelheim International GmbH, Boehringer Ingelheim Pharmaceuticals, Inc., or Eli Lilly and Company. The current U.S. prescribing information identifies JARDIANCE as a registered trademark of Boehringer Ingelheim International GmbH. References U.S. Food and Drug Administration (FDA) JARDIANCE (empagliflozin) Prescribing Information, current U.S. labeling. MedlinePlus — U.S. National Library of Medicine / National Institutes of Health Empagliflozin Drug Information. American Diabetes Association Standards of Care in Diabetes—2026: Pharmacologic Approaches to Glycemic Treatment. American Diabetes Association Standards of Care in Diabetes—2026: Cardiovascular Disease and Risk Management. Search terms Jardiance, Jardiance side effects, Jardiance how it works, empagliflozin, empagliflozin side effects, empagliflozin mechanism of action, SGLT2 inhibitor, SGLT2 inhibitors, Type 2 diabetes medication, Type 2 diabetes treatment, blood sugar, high blood sugar, diabetes medication, diabetes education, Jardiance and diabetes, how Jardiance works in the kidneys Hashtags #jardiance #empagliflozin #type2diabetes #diabetes #diabetesmedication #sglt2 #sglt2inhibitor #bloodsugar #diabetesmanagement #diabeteseducation